2024 sfb 221 Transregio Retreat

The 5th sfb 221 transregio221 annual retreat - of the 2nd funding period- will occur on May 2nd – May 3rd, 2024.

The retreat will take place at Schloss Hohenkammer in the district of Freising, in Upper Bavaria

The beautiful natural location on the water and the charming atmosphere of the castle will hopefully enable the participant to discuss and exchange scientific knowledge in a peceful and relaxing location  and to  stimulate new ideas in a relaxed and creative environment.

You can find the retreat program - and information to register - attached below.

Please register at your earliest convenience. 

The SFB 221 transregio Executive Board looks forward to welcoming you at  Schloss Hohenkammer. https://www.schlosshohenkammer.de




Thursday, May 2nd, 2024

Service projects       Chairs: t.b.a./t.b.a.

10.00 a.m.                Z01 - Büttner-Herold / Evert / Rosenwald

                                 Pathology workup of GvHD and GvL in mice and man

10.25 a.m.                Z02 -  Hoffmann / Winkler T. / Beilhack

                                 Animal engineering and complex transplantation models

10.50 a.m.                INF - Dandekar / Holler / Kehr / Kunz

                                 Data integration platform and systems medicine efforts to foster GvL & GvHD research


11.15 – 11.40 p.m.  Coffee break at "Gutshof Foyer", ground floor (t.b.c.)


Projects – Section A Chairs:  t.b.a./t.b.a.

11.40 a.m.                 A01 - Reimann / Kremer

                                 Deciphering the role of HLA-DO in immune responses after allogeneic stem cell transplantation

12.05 p.m.                A02 - Thomas / Herr

                                 Efficacy and safety of HLA-DPB1-specific T-cell receptors as mediators of graft-versus-leukemia effect

12.30 a.m.                A03 - Hudecek / Einsele

                                 Advanced CAR T cell engineering to augment the graft-versus-leukemia effect of allogeneic HSCT


12.55 – 02.10 p.m.   Lunch break at "Gutshof Restaurant", 1st floor


Projects – Section A Chairs:  t.b.a./t.b.a.

02.10 p.m.                 A04 - Bumm / Mokhtari / Stuhler

                                  Novel tri-specific T-cell activating antibodies for personalized graft-versus-leukemia therapy

02.35 p.m.                 A06 -  Mougiakakos / Mackensen

                                  Metabolic stress related immune alterations with impact on graft- versus-leukemia effect in allogeneic stem-cell transplantation

03.00 p.m.                 A07 – Harrer / Gattinoni

                                  Enhancing graft-versus-leukemia responses by donor- derived CAR-modified CD8+ T memory stem cells

03.25 p.m.                 A08 – Poeck / Schmidl

                                  Timed targeting of cGAS / STING to improve tissue regeneration and anti-tumor responses following allo-HSCT


03.50 – 04.10 p.m.     Coffee break at "Gutshof Foyer", ground floor (t.b.c.)


Projects – Section B Chairs:  t.b.a./t.b.a.

04.10 p.m.                  Associate Project -  Kilian Schober

                                   T cell receptors against immunodominant antigens in acute myeloid leukemia

04.35 p.m.                  B01 - Berberich-Siebelt / Spörl

                                   Therapeutic targeting of T-follicular cells in GvHD


05.15 – 06.30 p.m.      General assembly of PIs

07.30 p.m.                   Dinner for all participants at t.b.a.


Friday, May 3rd, 2024

  Projects – Section B Chairs:  t.b.a./t.b.a.

08.30 p.m.             B02 - Wajant

                             Targeting of TNFR2 and related molecules to separate GvHD from the GvL effect

08.55 a.m.             B03 – Hildner

                             Generation, molecular characteristics and effector mechanisms of CSF2+ T cells in graft-versus-host disease

09.20 a.m.             B04 - Distler / Jitschin

                             Aldehyde dehydrogenase 3A2 (ALDH3A2) as a novel regulator of inflammation and fibrotic tissue remodeling in sclerodermatous chronic graft-versus-host-                               disease

09.45 a.m.             B07 - Hoffmann / Rehli / Edinger

                              GvHD therapy with in vitro expanded donor regulatory T Cells


10.10 – 10.40 a.m.  Coffee break at "Gutshof Foyer", ground floor (t.b.c.)


 Projects – Section B Chairs:  t.b.a./t.b.a.

10.40 a.m.              B08 – Feuerer

                               Harnessing tissue homeostasis-promoting functions of specialized regulatory T cells in graft-versus- host disease

11.05 a.m.              B09 – Gomez de Agüero / Beilhack

                              Regulation of tissue-resident myeloid cells controlling acute and chronic GvHD

11.30 a.m.              B10 - Winkler T. / Winkler J. / Wolff

                              Dysregulations of the B- lymphocyte compartment leading to chronic GvHD


11.55 – 01.10 p.m. Lunch break at "Gutshof Restaurant", 1st floor


 Projects – Section B Chairs:  t.b.a./t.b.a.

01.10 p.m.              B11 – Zernecke-Madsen / Beilhack

                              Targeting the reciprocal interaction of GvHD and atherosclerosis after allogeneic HSCT

01.35 p.m.              B12 - Kreutz / Bruns

                               Regulation of the immune balance during allogeneic hematopoietic stem cell transplantation (HSCT) by vitamin D3

02.00 p.m.              B13 - Weber / Gessner / Holler

                               Enterococci in allogeneic stem cell transplantation – indicators of loss of diversity or true GvHD pathogens?

02.25 p.m.              B14 -  Zaiß

                               Role of EGF-like growth factors in immune regulation and tissue homeostasis during Graft versus Host (GvH) Disease


About 02.50 p.m.   Farewell – Coffee at "Gutshof Foyer", ground floor (t.b. c.)


To register, please contact:

Sabrina Bernhard-Linz

Universitätsklinikum Regensburg

Franz-Josef-Strauß-Allee 11

D - 93053 Regensburg

Phone: +49 (0) 941 944-5503



 Retreat Venue:

Schloss Hohenkammer GmbH – "Gutshof-Saal", 1st floor
Schlossstr. 20
85411 Hohenkammer
Phone: +49 (0)8137 934-0
Fax:     +49 (0)8137